The FDA is reviewing the safety of titanium dioxide in response to an April petition from EWG and other environmental and public health groups. This is the FDA’s first comprehensive review of titanium dioxide since 1973.

In some studies, E171 was given to animals in drinking water without the stabilizers that keep E171 suspended in the liquid. Without stabilizers, E171 can settle and prevent the ingredient from combining with surrounding ingredients.

Dispersion in the polymer: optimum dispersion should produce a good distribution and separation of titanium dioxide particles in the formulation.

Method of producing improved lithopone